OvaCis™

Ovarian Cancer

More than 90% of ovarian malignancies are classified as epithelial ovarian cancer (EOC), meaning it is epithelial in origin. Each year, a large number of women undergo an ovarian cystectomy to remove ovarian cysts that are thought to be benign. However, studies show that ovarian malignancy is unexpectedly encountered in 1 to 14% cases of laparoscopic cystectomies. Therefore, intra-operative testing for malignancy in women undergoing ovarian cystectomies is a critical component in optimal patient care, and particularly important for young women who wish to preserve their fertility.

About OvaCis™

OvaCis™ is a revolutionary, intra-operative assay for the detection of ovarian cancer. This Point-of-Care kit is first of its kind and simple to use. In three easy steps, surgeons are able to distinguish between benign and malignant ovarian cysts in the operating theatre during an ovarian cystectomy, with results available in just five minutes.

For more information, please go to OvaCis.com.sg .

How Does OvaCis™ Work?

The test works by identifying a protein biomarker found in ovarian cysts. A sample of fluid is taken from the patient during laparoscopic surgery and applied to the kit. The reagents combine to yield a colorimetric reaction which reveals if cancer is present (positive) or not (negative).

ovacis-diagram

Who Can Administer The Test?

OvaCis™ is designed for healthcare professionals, which includes clinicians, doctors and nurses. A user information leaflet is enclosed in each kit, detailing step-by-step instructions on how to apply the cyst sample into the kit.

How Useful is OvaCis™ in Practical Terms?

Frozen section – the current mainstay of intra-operative diagnosis of Epithelial Ovarian Cancer – is limited in achieving an accurate diagnosis. It is also time consuming (approximately 30 minutes to 1 hour) and not universally available, especially in developing countries. It is anticipated that OvaCis™ will revolutionise the practice of intra-operative surgical procedures. To date, no such kit exists, and it is envisaged that the test will routinely be used during ovarian cyst surgeries in the near future.

When Can OvaCis™ Be Used?

OvaCis™ is intended for the intra-operative detection of malignancy in women undergoing an ovarian cystectomy.

Is The Kit Portable?

OvaCis™ kits are available in 170×50 mm tray boxes, comprising syringes, reagents and a colorimetric chart that fits together in a compact portable, workstation.